This paper estimates the agricultural production water footprint (WF) of Chile, assessing green, blue and grey WFs of the main agricultural products for the main productive regions, taking into account climatic and soil differences. Chile’s agricultural production blue WF is geographically concentrated in the lower portion of the Northern Dry Pacific and Central Chile area, which present less water availability. Thus, irrigated agricultural production in Chile, a semiarid country, is characterized by high water stress. In this scenario, public policies are required to incentivize better water management in order to reduce water vulnerability while boosting development.